Different Areas of Carica papaya Linn Display Antifungal and Antimicrobial Activity

Ram Vighne

Department of Pharmaceutical Science, P. R. Pote Patil College of Pharmacy, Amravati, India.

Gaurav Mude *

Department of Pharmaceutical Science, P. R. Pote Patil College of Pharmacy, Amravati, India.

Chaitali Dangore

Department of Pharmaceutical Science, P. R. Pote Patil College of Pharmacy, Amravati, India.

Mona Kapse

Department of Pharmaceutical Science, P. R. Pote Patil College of Pharmacy, Amravati, India.

Sudarshan Behere

Department of Pharmaceutical Science, P. R. Pote Patil College of Pharmacy, Amravati, India.

*Author to whom correspondence should be addressed.


Abstract

The plants of Carica papaya are utilised for nutritional and therapeutic purposes. The phytochemical examination of the leaf extract of Carica papaya reveals all phytochemical elements, including saponin, flavonoid, glycoside, alkaloid, carbohydrates, tannins, and steroids. A systematic phytochemical analysis was used to check all extracts for the presence of phytochemical components. Free radical scavenging; wound healing; neuroprotection; diuretic; abortifacient; antifertility; anti-sickling; neuroprotective; diuretic; abortifacient; Antimicrobial properties of papaya seed extracts have been shown to be effective against B. cereus, S. faecalis, S. aureus, and a variety of bacterial pathogens. Anti-inflammatory properties of an ethanolic extract of Carica papaya L. leaf were investigated in rats with paw oedema. In order to create the extract, many solvents were used such as alcohol, methanol, and ethanol as well as aqueous extracts such as acetone and chloroform. The research indicates that the latex of papaya fruits exhibits substantial efficacy against Candida albicans. The well diffusion approach inhibits S. aureus more effectively than E. coli when using methanol extract. It has antifungal, antibacterial, anti-inflammatory, antioxidant, anti-diabetic, wound-healing, and analgesic properties, among others. According to the findings of this investigation, when given in doses of 50, 75, and 100 mg/ml, Carica papaya leaf extract had more antifungal activity against Colletotrichum gloeosporioides than Fusarium spp., Rhizopus stolonifer, and antibacterial activity than aqueous papaya leaf extract.

Keywords: Carica papaya, latex, Candida albicans


How to Cite

Vighne, R., Mude, G., Dangore, C., Kapse, M., & Behere, S. (2022). Different Areas of Carica papaya Linn Display Antifungal and Antimicrobial Activity. Asian Journal of Research in Medical and Pharmaceutical Sciences, 11(3), 22–31. https://doi.org/10.9734/ajrimps/2022/v11i330192

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