Study on of Ethanol and Aqueous Extracts of Embelia ribes for Anthelmintic Properties
Pinkey Rawal
Department of Pharmaceutical Chemistry, East West College of Pharmacy, Bangalore-560091, India.
C. Ramesh *
Department of Pharmacology, East West College of Pharmacy, Bangalore-560091, India.
B. A. Sowmya
Department of Pharmacology, East West College of Pharmacy, Bangalore-560091, India.
C. J. Ranjitha
Department of Pharmacology, East West College of Pharmacy, Bangalore-560091, India.
L. Anns Maria
Department of Pharmaceutical Chemistry, East West College of Pharmacy, Bangalore-560091, India.
*Author to whom correspondence should be addressed.
Abstract
Objectives: The present research study was conducted for the comparative evaluation of ethanol and aqueous extract of Embelia ribes for its in vitro anthelmintic properties.
Methods: The authenticated leaves of plant Embelia ribes were dried and powdered. The powdered drug was defatted with petroleum ether and a part of marc leftover was subjected to ethanol extraction using Soxhlet apparatus. Another part was subjected aqueous extraction using chloroform water. The ethanol and aqueous extracts of Embelia ribes was subjected to preliminary phytochemical investigation. Both the extracts were evaluated for in vitro anthelmintic properties using earthworms.
Results: The ethanol and aqueous extracts were revealed for the presence of alkaloids, glycosides, carbohydrates, flavonoids, tannins and phenols. The paralysis time and death time of worms were significantly reduced by the administration of ethanol and aqueous extracts of Embelia ribes.
Conclusion: The result of the present investigation confirms the anthelmintic property of Embelia ribes.
Keywords: Anthelmintic activity, Embelia ribes, piperazine citrate, Pheretima posthuma, earthworms