Standardization of Gandhaga Thailam: A Traditional Siddha Formulation for Skin Disorders
R. Sathish Adithya
Department of Nanju Maruthuvam, National Institute of Siddha, Chennai-47, India and Department of Siddha, Tamil Nadu Dr. MGR Medical University, Chennai-69, India.
E. M. Manikgantan *
Department of Siddha, Tamil Nadu Dr. MGR Medical University, Chennai-69, India.
N. Kabilan
Department of Siddha, Tamil Nadu Dr. MGR Medical University, Chennai-69, India.
S. Kanimozhi
Sri Sairam Siddha Medical College and Research Centre, Chennai-44, India.
*Author to whom correspondence should be addressed.
Abstract
Standardization is a part of Drug development process. Identifying the quality of a Siddha formulation is essential before it taken up for In vivo, In vitro studies and Clinical trials. Gandhaga thailam a Mineral based Siddha medicine to treat various ailments like Eczema, Ulcer, Peptic ulcer diseases etc. Test samples were extracted with acetone and briefly homogenized. Further filtration followed by addition of acetone to the test mixture. The test samples were heated using a rotary evaporator at a temperature not exceeding 40°C until almost complete evaporation of the solvent. HPTLC analysis reveals the presence of thirteen prominent peaks corresponds to the presence of thirteen versatile phytocomponents present within it. Rf value of the peaks ranges from 0.02 to 0.80. Study indicates that the Gandhaga Thailam is in standard quality, hence the preparation and purification processes of ingredients were done as per the literature. With these results Gandhaga thailam may be subjected to invitro and invivo toxicity studies in future. Results reveal the quality of the Medicine Gandhaga Thailam and may be the fingerprint for the future analysis on Gandhaga Thailam.
Keywords: Pharmacology, traditional medicine, Ghandhaga Thailam, siddha, standardization